Adsorption and desorption characteristic of macroporous resins D-0,D-0,AB-8,XAB-8 and D for diosmin in Galium verum was比较了D-0、D-0、AB-8、XAB-8、D 、聚酰胺等种吸附树脂对蓬子菜中活性成分香叶木苷diosmin的吸附和洗脱条件,在静态吸附研究的基础上,进行了动态实验,并且利用二次吸附对该成分进行了纯化。
Result: The typical equation of diosmin in rats plasma was Y= .0×0- C+.×0- ,the calibration curves of diosmin was linear果:香叶木苷血药浓度的回归方程为Y= .0×0- C+.×0- ,R=0.99 ,在0.~00μg.
Results:The linear ranges for Diosmin and Palrstroside were 0.0 0～.0 μg and 0.098～0.9 8 μg.果:香叶木苷在0.0 0~.0μg(r=0.999 9),喇叭茶苷在0.098~0.9 8μg(r=0.99 )与峰面积线性关系良好。
Studies on pharmacokinetics of diosmin in rats香叶木苷在大鼠体内的药代动力学研究
The plasma concentration of diosmin was determined by HPLC,and the pharmacokinetics parameters were calculated by p97 pkg-后,于不同时间点采血,用HPLC测定其血药浓度并用 p97软件拟合,求算药动学参数。