VPC most commonly occurs in bone, and has been known to be precipitated by cold weather, relative high hemoglobin concenVPC最常发生在骨部，常由气温下降、较高的血红蛋白浓度、脱水、感染、运动、潮湿、缺氧、酸中毒、应激和疲劳所诱发[2]。