The order of toxicity of hydrargyrum,plumbum,cuprum manganese,cadmium for artemia nauplius was Hg+>Pb+>Cu+>Mn+>Cd+. Hg-C毒性由强至弱依次为Hg+>Pb+>Cu+>Mn+>Cd+,Hg-Cu、Cu-Mn对卤虫幼体的联合作用表现为拮抗作用,Pb-Cu、Pb-Mn、Mn-Cd则表现为协同作用。