Bradykinin powerfully stimulates nociceptors, and an antagonist that blocks its receptors would certainly prevent those 那麽，能阻断缓激肽受体的拮抗剂，必定可以防止这些受体造成的痛觉受器活化。
Terri J,Zemin C,Sherif Y,et al.Role of angiotensin Ⅱ and bradykinin in experimental diabetic nephropathy.Funcational and文晖,林善锬.血管紧张素受体拮抗剂氯沙坦对糖尿病大鼠肾脏的保护作用.中华内科杂志,1999,38：157.