So abnormality of the ubiquitin-proteasome proteolytic pathway is closely related to many diseases, especially cancer.泛素介导的蛋白质降解途径的异常与许多疾病特别是肿瘤的发生密切相关。
The ubiquitin-proteasome proteolytic pathway, a major pathway for protein degradation in cells, plays a critical role in摘要泛素介导的蛋白质降解途径是降解细胞内蛋白质的主要途径，在维持细胞正常的蛋白质代谢中起着至关重要的作用。