Conclusion:"Caihe No. Ⅰ、Ⅱ " have therapeutic effect for frostbite in rabbit. "Caihe No. Ⅰ " is a decoction,while "Caihe “采和Ⅰ号”为煎剂、“采和Ⅱ号”为霜剂,后者在冬季治疗冻疮则更为方便。