Some leukemogenesis has been shown to be aberrance of epigenetic modification.

表观遗传修饰(epigeneticmodification),如DNA甲基化、组蛋白乙酰化和甲基化、RNA相关性沉默与细胞生长、分化、凋亡、转化及肿瘤进展相关基因的转录密切相关。