The results suggest that the Cys / 8 Ser mutant could evidently deprive PDI’s enzyme activity and seriously decrease the interchain cross-linking of PDI proteins.
The results suggest that the Cys / 8 Ser mutant could evidently deprive PDI’s enzyme activity and seriously decrease the interchain cross-linking of PDI proteins.
果表明，点突变（Cys / 8Ser）使PDI的酶活性丧失，从而导致PDI分子间并联能力明显下降。