Methods BALB/c mice were subcutaneously injected with 0.8mg of the synthesized peptide to produce the experimental autoimmune myocarditis (EAM) models.
Methods BALB/c mice were subcutaneously injected with 0.8mg of the synthesized peptide to produce the experimental autoimmune myocarditis (EAM) models.
方法:人工合成含心肌肌球蛋白抗原重链表位长度为30个氨基酸残基的多肽0.8mg,纯化多肽皮下免疫遗传易感BALB/c小鼠,建立自身免疫性心肌炎模型,检测TNF-α和cTnI病变期间的改变。