Activated SLP-7 will recruit and bind many downstream molecules including PLC-γ, Itk and Vav, whereas activated WASP will recruit and bind Grb-, Vav, WIP, Arp/ and Cdc-GTP, among others.
Activated SLP-7 will recruit and bind many downstream molecules including PLC-γ, Itk and Vav, whereas activated WASP will recruit and bind Grb-, Vav, WIP, Arp/ and Cdc-GTP, among others.
WASP活化后,通过募集结合Grb、Vav、WIP、Arp/ 和Cdc-GTP等,形成WASP信号转导复合体。