Results Flow cytometry results showed that IFN-γ,IFN-α,and TNF could up-regulate Fas,TRAIL,and DR expression on ECV 0.The most eminent result was that the percentage of Fas-expressing cells increased from 77.8% to 98.% by the modulation of IFN-γ.
Results Flow cytometry results showed that IFN-γ,IFN-α,and TNF could up-regulate Fas,TRAIL,and DR expression on ECV 0.The most eminent result was that the percentage of Fas-expressing cells increased from 77.8% to 98.% by the modulation of IFN-γ.
果静止ECV 0细胞膜表面有Fas、TRAIL、DR和DR等分子不同水平的组成性表达,IFN-γ、IFN-α和TNF等细胞因子刺激后,Fas、TRAIL和DR表达增加,其中IFN-γ对Fas的上调作用最显著,可使表达Fas细胞的阳性率从77.8%上升至98.%;