BPAGs which are located at the lamina lucida and hemidesmosome in BMZ are produced and secreted by the basal cells in the epidermis, including the main antigen BP 0 and the minor antigen BP80 which are critically important to the BP pathogenesis.
BPAGs which are located at the lamina lucida and hemidesmosome in BMZ are produced and secreted by the basal cells in the epidermis, including the main antigen BP 0 and the minor antigen BP80 which are critically important to the BP pathogenesis.
大疱性类天疱疮抗原(bullous pemphigoid antigen，BPAG)，由表皮基底细胞产生，分布于基底膜的透明层、半桥粒处。 其主要抗原为BPAG(BP 0)，位于基底细胞内半桥粒附着斑处，为高分子量( 0KD)的多肽。