Methods A proband and his 5 family members with T53→C in intron 1 and C59→A in intron 4 mutations of ApoM gene expression and their lipids were detected by polymerase chain reaction(PCR) direct DNA sequencing in a Han nationality Chinese family.
Methods A proband and his 5 family members with T53→C in intron 1 and C59→A in intron 4 mutations of ApoM gene expression and their lipids were detected by polymerase chain reaction(PCR) direct DNA sequencing in a Han nationality Chinese family.
方法应用聚合酶链反应DNA直接测序法,检测了1个携带ApoM基因1号内含子T53→C、4号内含子C59→A突变的先证者及其5名家系成员这2个位点的基因型及血脂情况。