Data indicates that and-Aβ antibodies play an important role in removing of brain amyloid depositions either in AD mice or in patients.
Data indicates that and-Aβ antibodies play an important role in removing of brain amyloid depositions either in AD mice or in patients.
构建了以β-片层结构的淀粉样蛋白(Aβ)及其可溶性与病理性突变体为抗原基因的DNA疫苗用于免疫小鼠,经过对免疫方案的探索和调整,结果能够打破其自身耐受,在外周血中诱发出较高滴度的抗-Aβ抗体。