Conclusion Mismatch repair genes hMLH and hMSH might play important role in maintaining stability of genome in normal skin and adnexal structures,abnormal hMLH and hMSH proteins may be involved in the carcinogenesis process and progression of CMM.
Conclusion Mismatch repair genes hMLH and hMSH might play important role in maintaining stability of genome in normal skin and adnexal structures,abnormal hMLH and hMSH proteins may be involved in the carcinogenesis process and progression of CMM.
论错配修复基因hMLH和hMSH蛋白在维护正常皮肤和皮肤附属器细胞基因组稳定性中可能发挥了重要作用,其异常可能参与了CMM发生和发展的过程。