Through the alkylation,partly reduction and Hoffman elimination of methylpyridine,theconjugated diene was obtained with 7.%～7.8% overall yield and 8%～90% ee.
Through the alkylation,partly reduction and Hoffman elimination of methylpyridine,theconjugated diene was obtained with 7.%～7.8% overall yield and 8%～90% ee.
从 甲基吡啶出发 ,通过烷基化、部分还原、霍夫曼消除等反应 ,合成了 N,N二甲基 [ N ,E]二烯胺 ,全合成总收率在 7. %～ 7.8% ,异构体纯度高达8 %～ 90 % .