METHODS 3,3-bis (dibenzyloxyphosphoiyl) propionic acid (5) and (6) were synthesized from tetraethyl methylene bisphosphonate via hydrolysis, chlorination of the acid, esterification, condensation, then 3,3-bis (dibenzyloxyphosphoryl) propanol (6) was obta
METHODS 3,3-bis (dibenzyloxyphosphoiyl) propionic acid (5) and (6) were synthesized from tetraethyl methylene bisphosphonate via hydrolysis, chlorination of the acid, esterification, condensation, then 3,3-bis (dibenzyloxyphosphoryl) propanol (6) was obta
方法以亚甲基偕二膦酸四乙酯(1)爲原料经水解、氯膦酰化、酯化、缩合得3,3－二（二苄氧膦酰基）丙酸(5)，随后选择性硼氢化还原得3,3－二（二苄氧膦酰基）丙醇(6)。