However, overexpression of WNK1 in HEK293 cells exerts no detectable effect on the activity of known substrates which indicates that WNK kinases belong to a novel signal pathway.
However, overexpression of WNK1 in HEK293 cells exerts no detectable effect on the activity of known substrates which indicates that WNK kinases belong to a novel signal pathway.
高表达WNK激酶家族的一个成员——WNK1在HEK293细胞中，没有检测到已知的作用底物生物活性的变化，说明WNK激酶属于一个新的信号传导通路。