A defective protein, which binds polyubiquitin chain (so-called degrading label) through its ε-amino group of Lys residue, is degraded in the proteasome.
A defective protein, which binds polyubiquitin chain (so-called degrading label) through its ε-amino group of Lys residue, is degraded in the proteasome.
对于需要清除的蛋白质,通过其赖氨酸残基侧链ε-氨基连接多聚泛素链(降解标签),继而在蛋白酶体中被降解。