Using interphase FISH,abnormalities of immunoglobulin heavy chain gene (IGH) were detected in 6/44 (13.6%) and 83/162 (51.2%) in the HL and NHL cases,respectively,while none was observed in 11 cases with a benign disease (P＜0.001).
Using interphase FISH,abnormalities of immunoglobulin heavy chain gene (IGH) were detected in 6/44 (13.6%) and 83/162 (51.2%) in the HL and NHL cases,respectively,while none was observed in 11 cases with a benign disease (P＜0.001).
间期FISH结果显示,HL的免疫球蛋白重链基因(IGH)异常的发生率为13．6%(6/44),NHL为51．2%(83/162),良性病变为0% (0/11),差异有统计学意义(P＜0．001)。