Results The conjugation rate, high molecular conjugate content of and the antibody titer induced with pneumococcus type 1 conjugate vaccine prepared by cyanogen bromide activation were significantly higher than that by amine reduction.
Results The conjugation rate, high molecular conjugate content of and the antibody titer induced with pneumococcus type 1 conjugate vaccine prepared by cyanogen bromide activation were significantly higher than that by amine reduction.
结果采用溴化氰活化法制备的结合物，较胺还原法具有较高的结合率及高分子结合物含量，免疫小鼠产生的抗体效价较胺还原法明显提高。