Müller cells are the regulon of retinal glutamate. glutamate transporter (GLAST) in Müller cells transport redundant glutamate in synapse grudge,then convert them to glutamine by glutamine synthetase(GS), which is called glutamate cycle in retina.
Müller cells are the regulon of retinal glutamate. glutamate transporter (GLAST) in Müller cells transport redundant glutamate in synapse grudge,then convert them to glutamine by glutamine synthetase(GS), which is called glutamate cycle in retina.
Müller细胞是视网膜谷氨酸浓度的调节单元,通过胞膜上的谷氨酸转运蛋白,主要是谷氨酸转运蛋白(glutamate transporter ,GLAST)摄取突触间过多的谷氨酸,由谷氨酰胺合成酶(glutamine synthetase,GS)转变为无兴奋性的谷氨酰胺。