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Conclusion The abnormal expression of hMLH1/hMSH2 and p53 might be involved in the carcinogenesis of lung cancer and correlated with differentiation stages and lymph node metastasis.

Conclusion The abnormal expression of hMLH1/hMSH2 and p53 might be involved in the carcinogenesis of lung cancer and correlated with differentiation stages and lymph node metastasis.

结论hMLH1及hMSH2基因的缺陷及p53的表达与肺癌的发生发展过程并与分化程度及有否淋巴结转移有关。