One of the key steps in those enzymatic reactions is that the distortion of corrin ring of the cofactor is induced by enzyme-proteins, and then the cobalt-carbon bond is broken to produce a ’-deoxyadenosyl radical and Br.
One of the key steps in those enzymatic reactions is that the distortion of corrin ring of the cofactor is induced by enzyme-proteins, and then the cobalt-carbon bond is broken to produce a ’-deoxyadenosyl radical and Br.
在这些酶反应中,酶诱导咕啉环构象改变,从而使Co-C键均裂产生’-脱氧腺苷自由基和Br被认为是催化反应的关键步骤。