Aims: In this study human colonic cancer cell line HT-29 stimulated by cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, interferon (IFN)-γ and LPS to appraise their effects on the expression of TLR4, MD-2 and responsiveness to LPS.
Aims: In this study human colonic cancer cell line HT-29 stimulated by cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, interferon (IFN)-γ and LPS to appraise their effects on the expression of TLR4, MD-2 and responsiveness to LPS.
目的:探讨以细胞因子肿瘤坏死因子(TNF)-α、白细胞介素(IL)-1β、干扰素(IFN)-γ和LPS刺激人结肠癌细胞系HT-29后,TLR4和MD-2的表达及其对LPS反应性的变化。