In this article, the principle and application of several gene mapping methods are discussed, including linkage analysis (parametric and nonparametric linkage analysis), association study and linkage disequilibrium analysis.
In this article, the principle and application of several gene mapping methods are discussed, including linkage analysis (parametric and nonparametric linkage analysis), association study and linkage disequilibrium analysis.
本文简要介绍疾病基因定位的几种常用分析方法，包括连锁分析法(参数法和非参数法)、关联分析和传递不平衡分析的基本原理和应用范围。