Conclusion The inactivation of suppressor gene p16 or low expression of protein p16 was associated with the progression,the degree of cell differentiation and neck metastasis in NPC,but it was not associated with the size of primary foci.
Conclusion The inactivation of suppressor gene p16 or low expression of protein p16 was associated with the progression,the degree of cell differentiation and neck metastasis in NPC,but it was not associated with the size of primary foci.
结论抑癌基因p16失活或p16蛋白低表达可能与鼻咽癌的发生、癌细胞的分化程度及颈淋巴结转移有关,而与鼻咽癌原发灶大小无关。